Anatech Newsletter-The Innovator

A source of technical information for your lab! Click to view past issues.

We Can Fix That!

A review of fixative solutions.

Why should you be using a xylene substitute?

Information regarding the use of xylene substitutes and how they can improve processing while making your lab safer!

H&E Staining

Hematoxylin and Eosin stain remains the cornerstone of tissue diagnostics. Re-view the procedure and learn to troubleshoot common H&E problems.

Special Stains, A Look at Some Old Favolrites.

Immunohistochemistry and molecular biology are truly advancing the diagnosis of diseases. However, histochemical special stains continue to play a role inthe pathology laboratory. Rediscover the utility of some of the most common special stains and meet the new additions to ANATECH’s family of “Really Special Stains”.

The Volatile Hematoxylin Market

Solve temporary supply issues with the cost effectivehematoxylin replacement stain, ANATECH’s Tango.

New Mucicarmine Makes Your Job EZ.

The high quality and availability of ANATECH’s new EZ dye and stain eliminates the problems previously associated with mucicarmine staining.

Making IHC Work for You.

Discover specific, practical tips for labs using glyoxal-based fixatives or receiving specimens so fixed.Learn when antigen retrieval is necessary for glyoxal-fixed tissue, and how to optimize your procedures.

Do You Ever See This?

There are a number of ways to prevent the so-called “nuclear halo artifact,” characterized by loss ofnuclear detail with a color shift from dark blue-violet to pale blue-gray. Choose the method that is right for your lab – from simple procedural adjustments to a variety of alternative fixatives.

Searching for Helicobacter

See a spectacular example of an H. pyloristain using replacements for Alcian yellow and toluidine blue.

Xylene Confirmed as a Reproductive Hazard.

A paper published in the Journal of the American Medical Associationpresents stunning evidence ofthe toxic effects on the fetus of some common workplace solvents. The reproductive study described in this newsletter confirms what safety experts have long suspected. There is a need to disseminate this information as widely as possible throughout our professional community.

Three Dyes, Three Dilemmas.

Dye supply problems, unreliable results and safety concerns create opportunities for improving histologystains. Three such examples are described in this publication: the shortage of Alcian blue; continuedsupply and quality problems of nuclear fast red; and the carcinogenicity of Congo red.

A Solution to the Irritating Problems of Formaldehyde.

The health hazards of formaldehyde are widely recognized, though often underestimated. In addition,environmental concerns and technical considerations argue strongly against its use. There is no reasonto continue using formalin when there are less hazardous fixatives available that will yield results asgood as, and usually better than, this traditional fixative.

From Patient to Embedding Center in Two Hours or Less.

Competition from other labs, pressures for faster turn-around time, and increased workload have created a demand for microwave fixation and processing. We show methods for producing consistent,high quality results using microwave technology.

The Artifact of Managed Health Care.

Managed health care has put pressures on laboratories that traditional technologies cannot accommo-date. Lack of adequate fixation has led to a group of artifacts virtually unknown years ago, that we arenow attempting to overcome. Discover procedures which prove that high quality specimens and fastturn-around time are not mutually exclusive goals.

ANATECH LTD Announces New Fixative to Replace B-5.

Despite technical drawbacks and environmental concerns, B-5 continues to be the fixative of choicefor certain tissues in many laboratories. ANATECH’s replacement product, Z-5, surpasses the goodqualities of B-5 while eliminating its technical disadvantages and drastically reducing its environmentalliability.